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Supercritical fluids, particle formation

Formation of pharmaceutical particles by expansion of a supercritical solution.

The figure shows the expansion path along an adiabate in the RESS process (Rapid Expansion of a Superciritcal Solution) as well as snapshots of the simulation system.


https://doi.org/10.1016/j.supflu.2010.08.010

https://doi.org/10.1021/jp906478z